Explore Faculty Labs in Biological Sciences at UMass Lowell

Biology faculty, postdoctoral scholars and students conduct research in four broad, overlapping areas:Ìý

Please explore each area below to learn more about faculty labs and research facilities, or view all faculty labs.

â Biophysics & Physiology

Study how bodies function at every level (molecules, cells, tissues, and organs) to help develop methods to treat diseases.

Imaging neurons can help understand basis of neurodegenerative disease.

Our labs have expertise spanning various aspects of muscle physiology, feeding and locomotion, physiological ecology, molecular biomechanics, structural enzymology, and neurodegenerative diseases.


  • Structural Biology, Bioinformatics, Enzymology, Immune Responses

  • Biomechanics, Muscle Physiology, Ecomorphology

  • Molecular Motors, Cellular Motility & Muscle Contraction
  • Matthew Sasaki
    Ecology, Evolutionary Biology, Global Change
  • Thomas Shea
    Cell Biology

Our labs participate in theÌýUMass Movement Research Center (UMOVE)Ìýand meet regularly with the UMass Lowell student chapter of The Biophysical Society.

â Cell and Developmental Biology

Seek to understand the inner workings of the cell, how cell fate is determined and how organismal complexity arises during embryogenesis and cellular differentiation.Ìý

Cell culture is an important technique in biotechnology research.

Our labs have expertise in many approaches, including classical genetics, genetic engineering, molecular biology, immunology, biophysics, cytology, and bioinformatics. We employ these techniques in a diverse range of research systems that span the animal kingdom: nematodes, fruit flies, fish, chick, mice, and mammalian cells in culture.

  • Paul Bryce
    Immunology, allergy, therapeutics, inflammation
  • Craniofacial Development and Evolution
  • Molecular and Developmental Biology

  • Epigenetics, longevity, chromatin, molecular genetics
  • Thomas Shea
    Cell Biology

  • Immunology, B cells, Ecoimmunology, Host-parasite interactions, Comparative immunology
  • Drosophila, cell-cell communication, Wnt/Wg signaling, genetics, cell and developmental biology

Labs in these areas are part of theÌýCenter for Pathogen Research and TrainingÌý(CPRT).

â Ecology & Evolution

Investigate the origin and maintenance of diversity across all levels of biological organization, from genomes to ecosystems.Ìý

A student from the Steinel lab crouches while moving fish from a mesh bucket to open water in Alaska.

Labs in our department have expertise in evolutionary genomics, invertebrate ecology and evolution, climate change, biodiversity monitoring, evolutionary biomechanics, ecomorphology, phylogenetics, evo-devo, and host-parasite coevolution.


  • Bioinformatics, Evolution and Environmental Genomics
  • Craniofacial Development and Evolution

  • Molecular Evolution & Systematic Biology

  • Global Change, Infectious Disease, Genomics, Bioinformatics

  • Evolution, Biodiversity, Phylogenetics, Herpetology

  • Invertebrate Zoology

  • Biomechanics, Muscle Physiology, Ecomorphology
  • Matthew Sasaki
    Ecology, Evolutionary Biology, Global Change

  • Immunology, B cells, Ecoimmunology, Host-parasite interactions, Comparative Immunology

Undergraduates excited to do research in this area are encouraged to pursue the Ecology, Evolution and Organismal Biology degree option.Ìý

â Genetics, Genomics & Bioinformatics

Understand the molecular basis of organismal traits using a range of molecular genetic and genomic technologies, alongside computational analyses of the resulting large-scale data.Ìý

Melamed lab integrates diverse biomedical data for drug repurposing.

Research goals include understanding the evolution of adaptations and species, investigating why some individuals are vulnerable to disease, discovering pathogens based on genomic data and investigating the molecular nature of gene regulation.


  • Bioinformatics, Evolution and Environmental Genomics

  • Molecular Evolution & Systematic Biology

  • Global Change, Infectious Disease, Genomics, Bioinformatics

  • Structural Biology, Bioinformatics, Enzymology, Immune Responses
  • Craniofacial Development and Evolution

  • Epigenetics, Longevity, Chromatin, Molecular Genetics

  • Computational Biology, Cancer Genomics, Data Science, Biomedical Informatics
  • Drosophila, Cell-Cell Communication, Wnt/Wg Signaling, Genetics, Cell and Developmental Biology

Undergraduates and Master's students interested in joining this research may consider enrolling in our program options in Bioinformatics or Biotechnology.

Brooke Sienkiewicz diving in Belize.
Brooke Sienkiewicz
Applied Biology Ph.D.

Brooke Sienkiewicz conducts fieldwork in the Caribbean as part of her Ph.D. program.

I’m so grateful that I get to do field research in the Caribbean.
Read More About Brooke Sienkiewicz 

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